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Ovarian Cancer

This section will take a look at the subject of Ovarian Cancer. Other topics that contain information for women can be found further down the page.

Ovarian cancer is cancer that begins in the ovaries. In women, the ovaries produce eggs (ova) for reproduction. Cancer can also begin in the fallopian tubes.

There are several types of ovarian cancer. Ovarian cancer that begins on the surface of the ovary (epithelial carcinoma) is the most common type.

By the time symptoms appear, the ovarian tumor may have grown large enough to shed cancer cells throughout the abdomen. At such an advanced stage, the cancer is more difficult to cure.

Ovarian cancer is staged from I through IV, which indicates earliest to most advanced. Ovarian cancer causes more deaths than any other type of cancer affecting the reproductive system. Ovarian cancer can be treated with surgery, chemotherapy, or radiation therapy.

The presence of a mutation in any of these genes does not predict with absolute certainty that either breast cancer or ovarian cancer will occur.

Your chances of surviving ovarian cancer are better if the cancer is found early. But because the disease is difficult to detect in its early stage, only about 29 percent of ovarian cancers are found before tumor growth has spread.

Patients with a personal history of breast cancer, or a family history of breast and/or ovarian cancer, may have an elevated risk.

Ovarian cancer is classified as Stage II when cancer has spread from one or both ovaries to other parts within the pelvis, e.g. uterus, fallopian tubes.

Ovarian cancers shed malignant cells into the naturally occurring fluid within the abdominal cavity. An exploratory surgical procedure called laparotomy generally is required for the definitive diagnosis of ovarian cancer.

Sometimes, ovarian cancer occurs in more than one family member but isn't the result of any known inherited gene alteration. Having some family history of ovarian cancer increases your risk of the disease, but not to the same degree as does having an inherited genetic defect.

Lifetime number of ovulations are closely associated with ovarian cancer risk so that nulliparity, few pregnancies, early menarche, and late menopause, are all risk factors.

Because ovarian cancer usually develops in the thin lining of the abdominal cavity that covers the ovaries, women who have had their ovaries removed can still get a similar but less common form of cancer called primary peritoneal cancer.

Events in a woman’s life that inhibit the release of eggs from the ovaries appear protective against developing ovarian cancer. The lifetime probability of ovarian cancer increases from about 1.6% in a 35-year-old woman without a family history of ovarian cancer to about 5% if she has 1 relative and 7% if she has 2 relatives with ovarian cancer.

 

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